Polyglandular autoimmune syndromes

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Polyglandular Autoimmune Syndromes (pga)

Definition of PGA PGA involve multiple endocrine gland insufficiencies (minimum two), being frequently associated with diseases of non-endocrine organs, and occur in individual patients and their families.1,2 The autoimmune endocrine associations recognise more generics: autoimmune polyglandular syndromes (APS), autoimmune polyendocrine disease (APD), polyglandular failure syndromes (PFS), and ...

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Polyglandular autoimmune syndrome type II.

The polyglandular autoimmune syndromes (PAS) comprise a wide spectrum of autoimmune disorders. There exist a juvenile (PAS I) and an adult type (PAS II). The nature of PAS has been based on the presence of lymphocyte infiltration in the affected gland, organ-specific antibodies in the serum, cellular immune defects and an association with the human leucocyte antigen (HLA) DR/DQ genes or immune ...

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Polyglandular autoimmune syndrome-type I.

Polyglandular autoimmune syndrome type I is a rare disorder characterized by mucocutaneous candidiasis (MC), hypoparathyroidism (HP) and adrenal insufficiency , requiring regular follow up as the components of the syndrome appear at different age groups. We report a six and half year boy having this syndrome and presenting with MC, HP and ectodermal dystrophy.

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Autoimmune polyglandular syndrome, type II.

The combination of autoimmune adrenal insufficiency with autoimmune thyroid disease and/or type 1 autoimmune diabetes mellitus defines autoimmune polyglandular syndrome, type II. The conditions may occur in any order, and diagnosis is confounded by the nonspecific nature of the symptoms of adrenal insufficiency and hypothyroidism. The disorder is not common, but consequences can be life threate...

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Type III Polyglandular Autoimmune Syndromes in children with type 1 diabetes mellitus.

INTRODUCTION Type III Polyglandular Autoimmune Syndrome (PAS III) is composed of autoimmune thyroid diseases associated with endocrinopathy other than adrenal insufficiency. This syndrome is associated with organ-specific and organ-nonspecific or systemic autoimmune diseases. The frequency of PAS syndromes in diabetic children is unknown. OBJECTIVES The aim of the study was to evaluate the in...

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ژورنال

عنوان ژورنال: European Journal of Endocrinology

سال: 2009

ISSN: 0804-4643,1479-683X

DOI: 10.1530/eje-09-0044